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Anti-Diabetic Effects of the Senolytic Agent DasatinibThis retrospective cohort study suggests dasatinib and related senolytic drugs have an anti-diabetic effect comparable to, or greater than, contemporary anti-diabetic medications in patients with pre-existing T2DM.
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Dr James O'Keefe notes regular moderate leisure sports activities lowers all-cause mortality and should be promoted.
Read the article, U-Shaped Association Between Duration of Sports Activities and Mortality: Copenhagen City Heart Study
Dr Alan Rozanski finds the combined assessment of BMI and exercise ability and capacity provides risk stratification of future mortality risk among patients referred for radionuclide stress testing.
Read the article, Synergistic Assessment of Mortality Risk According to Body Mass Index and Exercise Ability and Capacity in Patients Referred for Radionuclide Stress Testing
Dr Patrick O'Leary finds stem cell injection was associated with improved left ventricular ejection fraction at 6 months post-cone reconstruction.
Read the article, Cone Reconstruction for Ebstein Anomaly: Ventricular Remodeling and Preliminary Impact of Stem Cell Therapy
Dr Kurt Pfeifer gives a brief introduction to consensus recommendations from SPAQI in the area of preoperative management of gastroenterology and pulmonary medicine.
Read the article, Preoperative Management of Gastrointestinal and Pulmonary Medications: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement
Mr Abdulah Mahayni finds robust supportive data for the algorithm to predict 5- and 10-year mortality risks for patients undergoing cardiac surgery.
Read the article, Electrocardiography-Based Artificial Intelligence Algorithm Aids in Prediction of Lon-term Mortality After Cardiac Surgery
Dr Matthew Warner finds that the development and implementation of a comprehensive patient blood management program was associated with substantial reductions in transfusion utilization and improved clinical outcomes.
Read the article, Implementation of a Comprehensive Patient Blood Management Program for Hospitalized Patients at a Large United States Medical Center
Dr Fatima Cody Stanford finds that prescriptions for anti-obesity medications are significantly underutilized in the treatment of obesity.
Read the article, Treatment of Obesity: Pharmacotherapy Trends of Office-Based Visits in the United States from 2011 to 2016
Dr Aashish Gupta reviews a robust, easy-to-use, model for systematically evaluating patients presenting to acute care settings with COVID-19 infection.
Read the article, Development and Validation of a Multivariable Risk Prediction Model for COVID-19 Mortality in the Southern United States
Dr Amir Lerman notes noninvasive monitoring of endothelial function and identification of high-risk patients who may require specific therapies has the potential to improve morbidity and mortality associated with subsequent inflammation, cytokine storm, and multi-organ involvement.
Read the article, Viral Endothelial Dysfunction: A Unifying Mechanism for COVID-19
Dr Caleb Scheckel offers insights into biosimilars and generic medications with a focus on improving drug costs for cancer patients.
Read the article, Generics and Biosimilars: Barriers and Opportunities
Dr Felice Gersh notes postmenopausal women might benefit from hormone replacement therapy to counteract adverse health effects from estradiol deficiency.
Read the article, The Renin-Angiotensin-Aldosterone System in Postmenopausal Women: The Promise of Hormone Therapy
Dr Zubin Master finds physicians could benefit from resources that aid in responding to the relational needs of patients approaching them for advice on using unproven stem cell treatments.
Read the article, Academic Physician Specialists' Approaches to Counseling Patients Interested in Unproven Stem Cell and Regenerative Therapies — A Qualitative Analysis
Dr Arianna Pani examines the serologic response to the COVID-19 vaccination 14 days after receiving a second dose.
Read the article, Results of the RENAISSANCE Study: REsponse to BNT162b2 COVID-19 VacciNe–short- And long-term Immune reSponSe evAluatioN in health Care workErs
Dr Dusan Petrovic finds an association between caffeine intake and plasma lipids, a major risk indicator in cardiovascular disease.
Read the article, Investigating the Relations Between Caffeine-Derived Metabolites and Plasma Lipids in 2 Population-Based Studies
Dr Tufia Haddad shares experiences with initiating virtual health care during the height of the COVID-19 pandemic with minority populations.
Read the article, Avoiding the "Faux Equalizer"
Dr Brian Linder discusses evaluation of, and surgical and nonsurgical treatment options for, pelvic organ prolapse.
Read the article, Evaluation and Management of Pelvic Organ Prolapse
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This month: Medical Images from 3 Patients
MCP Pioneers and Legends
Dr. R. Scott Wright, a Professor of Medicine in Cardiology facilitates a conversation with Dr. David R. Holmes, Jr. MD, a Distinguished Professor of Medicine in Cardiology, both at Mayo Clinic in Rochester, Minnesota. They reminisce about past challenges and review current and future state of the art treatments emanating from the interventional cath lab, and offer hope for future patients. They touch on the invention of the Watchman device, the evolution of TAVR, and recommend maintaining a sense of wonder.
Featuring Dr Carlo Brugnara, a Professor of Pathology from Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, interviewed by our Associate Editor, Dr Vincent Rajkumar.
Dr P. James B. Dyck facilitates a conversation with a scholar in Pioneers and Legends in Medicine with his father, Dr Peter J. Dyck.
Dr Karl Nath facilitates a conversation with a scholar in Pioneers and Legends in Medicine. Watch the feature with Dr Donald Scholz.
Dr Karl Nath is delighted to invite you to view this brief conversation with Dr Robert Kyle in the series Pioneers and Legends in Medicine.
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Dr Karl Nath discusses the Editor's Choice and Highlighted articles in the December 2021 issue.
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